3,8-Diazaspiro[4.5]decan-2-one HCl
2,8-diazaspiro[4.5]decan-3-one
CAS: 561314-57-6
Molecular Formula: C8H14N2O
3,8-Diazaspiro[4.5]decan-2-one HCl - Names and Identifiers
| Name | 2,8-diazaspiro[4.5]decan-3-one |
| Synonyms | 2,8-Diazaspiro[4.5]decan-... 2,8-Diazaspiro[4.5]decan-3-on 2,8-diazaspiro[4,5]decan-3-one 2,8-diazaspiro[4.5]decan-3-one 2,8-DIAZASPIRO[4.5]DECAN-3-ONE 3,8-Diazaspiro[4.5]decan-2-one HCl |
| CAS | 561314-57-6 |
| InChI | InChI=1/C8H14N2O/c11-7-5-8(6-10-7)1-3-9-4-2-8/h9H,1-6H2,(H,10,11) |
3,8-Diazaspiro[4.5]decan-2-one HCl - Physico-chemical Properties
| Molecular Formula | C8H14N2O |
| Molar Mass | 154.21 |
| Density | 1.12±0.1 g/cm3(Predicted) |
| Boling Point | 360.1±42.0 °C(Predicted) |
| Flash Point | 170.81°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 16.29±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | IRRITANT |
| Refractive Index | 1.533 |
| MDL | MFCD16039369 |
3,8-Diazaspiro[4.5]decan-2-one HCl - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29339900 |
3,8-Diazaspiro[4.5]decan-2-one HCl - Introduction
2,8-diazaspiro[4.5]decan-3-one(2,8-diazaspiro[4.5]decan-3-one) is an organic compound. It has the formula C≡H≡N₂ and has the appearance of a white or light yellow solid. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White or light yellow solid.
-Melting point: about 60-70 degrees Celsius.
-Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Stability: Stable under conventional experimental conditions.
Use:
-Chemical synthesis intermediate: 2,8-diazaspiro[4.5]decan-3-one can be used as a chemical synthesis intermediate for the synthesis of other organic compounds.
-Pharmaceutical research: The compound and its derivatives are used in the synthesis of various drugs in the field of pharmaceutical research.
Preparation Method:
2,8-diazaspiro[4.5]decan-3-one can be synthesized by the following steps:
1. Through an appropriate reaction, acetone (propanone) is converted to N-tert-butoxykanin (N-tert-butoxycarbonylketimine).
2. N-tert-butoxykanin reacts with aminobutanol (aminobutanol) under appropriate conditions to generate 2,8-diazaspiro[4.5]decan-3-one.
Safety Information:
-Wear protective gloves and goggles when using.
-Avoid contact with skin, eyes and respiratory tract.
-Use in a well-ventilated place to avoid inhaling harmful gases.
-Observe laboratory safety procedures.
It should be noted that the information provided above is for reference only. When using or handling the compound, please refer to the specific chemical literature or the guidance provided by professional institutions.
Nature:
-Appearance: White or light yellow solid.
-Melting point: about 60-70 degrees Celsius.
-Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Stability: Stable under conventional experimental conditions.
Use:
-Chemical synthesis intermediate: 2,8-diazaspiro[4.5]decan-3-one can be used as a chemical synthesis intermediate for the synthesis of other organic compounds.
-Pharmaceutical research: The compound and its derivatives are used in the synthesis of various drugs in the field of pharmaceutical research.
Preparation Method:
2,8-diazaspiro[4.5]decan-3-one can be synthesized by the following steps:
1. Through an appropriate reaction, acetone (propanone) is converted to N-tert-butoxykanin (N-tert-butoxycarbonylketimine).
2. N-tert-butoxykanin reacts with aminobutanol (aminobutanol) under appropriate conditions to generate 2,8-diazaspiro[4.5]decan-3-one.
Safety Information:
-Wear protective gloves and goggles when using.
-Avoid contact with skin, eyes and respiratory tract.
-Use in a well-ventilated place to avoid inhaling harmful gases.
-Observe laboratory safety procedures.
It should be noted that the information provided above is for reference only. When using or handling the compound, please refer to the specific chemical literature or the guidance provided by professional institutions.
Last Update：2024-04-09 19:05:50
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